1neg Summary


Crystal Structure Analysis of N-and C-terminal labeled SH3-domain of alpha-Chicken Spectrin

The structure was published by Mueller, U., Buessow, K., Diehl, A., et al., Niesen, F.H., Nyarsik, L., and Heinemann, U., in 2003 in a paper entitled "Rapid purification and crystal structure analysis of a small protein carrying two terminal affinity tags" (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.3 Å and deposited in 2002.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of Spectrin alpha chain, brain. This molecule has the UniProt identifier P07751 (SPTN1_CHICK)search. The sample contained 83 residues which is < 90% of the natural sequence. Out of 83 residues 65 were observed and are deposited in the PDB.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Spectrin alpha chain, brain P07751 (965-1024) (SPTN1_CHICK)search Gallus gallussearch < 90% 83 78%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P07751 (965 - 1024) Spectrin alpha chain, brain Gallus gallus

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A SH3-domainsearch SH3 Domainssearch SH3 domainsearch, Spectrin repeatsearch

Chain ID Biological process (GO)
A (P07751) endocytosissearch

Chain InterPro annotation
A SH3 domainsearch Spectrin alpha chain, SH3 domainsearch Endophilin-Asearch