 |
PDBe Entry: 1ndy 
Crystal Structure of Adenosine Deaminase Complexed with FR230513
 |
hydrolase
|
|
X-RAY DIFFRACTION
|
|
Resolution: 2.0 Å, R-factor: 20.3%, Free R-factor: 21.0%, Spacegroup: P 43 21 2
|
|
09/12/2003, deposition: 09/12/2002, last revision: 24/02/2009
|
|
Kinoshita, T.
|
A highly potent non-nucleoside adenosine deaminase inhibitor: efficient drug discovery by intentional lead hybridization
J.AM.CHEM.SOC. vol:126, pag:34-35 (2004) [PubMed ID 14709046 ]
|
|
SBDD, TIM-barrel, hydrolase
|
|
3.5.4.4 ExPASy BRENDA (A)
|
|
Bos taurus(cattle) 9913(A)
|
|
Adenosine deaminase (EC 3.5.4.4) (Adenosine aminohydrolase) P56658 (A)
|
|
A
|
|
1ndv, 1ndw, 1ndz
|
| A |
Adenosine Deaminase |
Protein |
P56658 (ADA_BOVIN)
|
356 |
98% |
|
| A |
ZINC ION |
ZN
|
| A |
1-((1R)-1-(HYDROXYMETHYL)-3-(1-NAPHTHYL)PROPYL)-1H-IMIDAZOLE-4-CARBOXAMIDE |
FR3
|
|
|
