1ndo Summary

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NAPHTHALENE 1,2-DIOXYGENASE

The structure was published by Kauppi, B., Lee, K., Carredano, E., et al., Gibson, D.T., Eklund, H., and Ramaswamy, S., in 1998 in a paper entitled "Structure of an aromatic-ring-hydroxylating dioxygenase-naphthalene 1,2-dioxygenase." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.25 Å and deposited in 1998.

The experimental data on which the structure is based was also deposited.

This PDB entry contains a complex of 2 biomacromolecules, namely NAPHTHALENE 1,2-DIOXYGENASE.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms heterohexamers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A NAPHTHALENE 1,2-DIOXYGENASE P0A110 (1-449) (NDOB_PSEPU)search Pseudomonas putidasearch 100% 449 99%
C NAPHTHALENE 1,2-DIOXYGENASE P0A110 (1-449) (NDOB_PSEPU)search Pseudomonas putidasearch 100% 449 99%
E NAPHTHALENE 1,2-DIOXYGENASE P0A110 (1-449) (NDOB_PSEPU)search Pseudomonas putidasearch 100% 449 99%
B NAPHTHALENE 1,2-DIOXYGENASE P0A112 (1-194) (NDOC_PSEPU)search Pseudomonas putidasearch 100% 194 99%
D NAPHTHALENE 1,2-DIOXYGENASE P0A112 (1-194) (NDOC_PSEPU)search Pseudomonas putidasearch 100% 194 99%
F NAPHTHALENE 1,2-DIOXYGENASE P0A112 (1-194) (NDOC_PSEPU)search Pseudomonas putidasearch 100% 194 99%


This entry contains 2 unique UniProt proteins:

UniProt accession Name Organism PDB
P0A110 (1 - 449) NAPHTHALENE 1,2-DIOXYGENASE Pseudomonas putida
P0A112 (1 - 194) NAPHTHALENE 1,2-DIOXYGENASE Pseudomonas putida

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A, C, E (P0A110) Ring hydroxylating alpha subunit ISP domainsearch, Ring hydroxylating alpha subunit catalytic domainsearch Naphthalene 1,2-dioxygenase Alpha Subunit; Chain A, domain 1search, 'Rieske'-like iron-sulphur domainssearch PF00355: Rieske [2Fe-2S] domainsearch, PF00848: Ring hydroxylating alpha subunit (catalytic domain)search
B, D, F (P0A112) Ring hydroxylating beta subunitsearch Nuclear Transport Factor 2; Chain: A,search PF00866: Ring hydroxylating beta subunitsearch

Chain ID Biological process (GO) Molecular function (GO)
A, C, E (P0A110) cellular aromatic compound metabolic processsearch oxidation-reduction processsearch aromatic compound catabolic processsearch oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygensearch iron ion bindingsearch oxidoreductase activitysearch oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donorsearch 2 iron, 2 sulfur cluster bindingsearch protein bindingsearch iron-sulfur cluster bindingsearch metal ion bindingsearch dioxygenase activitysearch naphthalene 1,2-dioxygenase activitysearch
B, D, F (P0A112) cellular aromatic compound metabolic processsearch oxidation-reduction processsearch aromatic compound catabolic processsearch catalytic activitysearch protein bindingsearch dioxygenase activitysearch oxidoreductase activitysearch naphthalene 1,2-dioxygenase activitysearch

Chain InterPro annotation
A, C, E Aromatic-ring-hydroxylating dioxygenase, alpha subunitsearch Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domainsearch Aromatic-ring-hydroxylating dioxygenase, 2Fe-2S-binding sitesearch Rieske [2Fe-2S] iron-sulphur domainsearch
B, D, F Aromatic-ring-hydroxylating dioxygenase, beta subunitsearch