› 1n9j

Solution NMR

Solution Structure of the 3D domain swapped dimer of Stefin A

Released:
DOI: 10.2210/pdb1n9j/pdb
PDB entry 1n9j coloured by chain, front view.
PDB entry 1n9j coloured by chain, side view.
PDB entry 1n9j coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Three-dimensional domain swapping in the folded and molten-globule states of cystatins, an amyloid-forming structural superfamily.
Staniforth RA, Giannini S, Higgins LD, Conroy MJ, Hounslow AM, Jerala R, Craven CJ, Waltho JP
EMBO J 20 4774-81 (2001)
PMID: 11532941

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-133897 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cystatin-A Chains: A, B
Molecule details ›
Chains: A, B
Length: 98 amino acids
Theoretical weight: 11.02 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P01040 (Residues: 1-98; Coverage: 100%)
Gene names: CSTA, STF1, STFA
Sequence domains: Cystatin domain
Structure domains: Nuclear Transport Factor 2; Chain: A,

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

22 review citations

3D domain swapping: as domains continue to swap.
Liu et al. (2002)
21 more

4 mentions without citation

Open interface and large quaternary structure movements in 3D domain swapped proteins: insights from molecular dynamics simulations of the C-terminal swapped dimer of ribonuclease A.
Merlino et al. (2005)
3 more