Crystal Structure of the complex between the Orphan Nuclear Hormone Receptor ROR(alpha)-LBD and Cholesterol
The structure was published by Kallen, J.A., Schlaeppi, J.M., Bitsch, F., et al., Geiser, M., Delhon, I., and Fournier, B., in 2002 in a paper entitled "X-ray Structure of hROR(alpha) LBD at 1.63A: Structural and Functional data that Cholesterol or a Cholesterol derivative is the natural ligand of ROR(alpha)" (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 1.63 Å and deposited in 2002.
The experimental data on which the structure is based was also deposited.
The PDB entry contains the structure of Nuclear receptor ROR-alpha. This molecule has the UniProt identifier P35398 (RORA_HUMAN). The sample contained 270 residues which is < 90% of the natural sequence. Out of 270 residues 251 were observed and are deposited in the PDB.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule is most likely monomeric.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: