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EBI PDBe PDBeView

PDBe Entry: 1n78 view

Crystal structure of Thermus thermophilus glutamyl-tRNA synthetase complexed with tRNA(Glu) and glutamol-AMP.
Summary
Header ligase/RNAsearch
Method X-RAY DIFFRACTION
Experiment Resolution: 2.1 Å, R-factor: 22.0%, Free R-factor: 25.9%, Spacegroup: C 2 2 21
Released 25/02/2003, deposition: 13/11/2002, last revision: 24/02/2009
Authors Sekine, S.search; Nureki, O.search; Dubois, D.Y.search; Bernier, S.search; Chenevert, R.search; Lapointe, J.search; Vassylyev, D.G.search; Yokoyama, S.search; RIKEN Structural Genomics/Proteomics Initiative (RSGI)search
Primary citation ATP binding by glutamyl-tRNA synthetase is switched to the productive mode by tRNA binding
EMBO J.search vol:22, pag:676-688 (2003) [PubMed ID 12554668 ]search
Keywords ERS/tRNA/GOAsearch, RIKEN Structural Genomics/Proteomics Initiativesearch, RSGIsearch, Structural Genomicssearch, ligase/RNA COMPLEXsearch
EC 6.1.1.17 ExPASy BRENDA search (A B)
Organism Thermus thermophilus 274search(A B)
UniProt Glutamyl-tRNA synthetase (EC 6.1.1.17) (Glutamate--tRNA ligase) (GluRS) P27000search (A B)
Solvent A, B, C, D
Related entries 1g59, 1gln, 1j09, 1n75, 1n77
Polymers
Id Name Type UniProt Residues Observed
C, D tRNA(Glu) RNA
75 100%
A, B Glutamyl-tRNA synthetase Protein P27000 (SYE_THET8)search
 468 100%
Heterogens
Id Name Ligands
C, D MAGNESIUM ION MG search
A, B GLUTAMOL-AMP GOM search
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