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PDBe Entry: 1n4s 
Protein Geranylgeranyltransferase type-I Complexed with GGPP and a Geranylgeranylated KKKSKTKCVIL Peptide Product
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TRANSFERASE
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X-RAY DIFFRACTION
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Resolution: 2.6 Å, R-factor: 19.4%, Free R-factor: 21.4%, Spacegroup: C 1 2 1
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18/11/2003, deposition: 01/11/2002, last revision: 12/05/2009
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Taylor, J.S.; Reid, T.S.; Casey, P.J.; Beese, L.S.
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Structure of mammalian protein geranylgeranyltransferase type-I
EMBO J. vol:22, pag:5963-5974 (2003) [PubMed ID 14609943 ]
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protein geranylgeranyltransferase type-I, GGTase, geranylgeranyl, protein prenylation, CaaX, lipid modification, rap2b
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2.5.1.58 ExPASy BRENDA (A C E G I K), 2.5.1.59 ExPASy BRENDA (A B C D E F G H I J K L)
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Rattus norvegicus(Norway rat) 10116(A C E G I K B D F H J L)
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Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (EC 2.5.1.58) (EC 2.5.1.59) (CAAX farnesyltransferase subunit alpha) (Ras proteins prenyltransferase alpha) (FTase-alpha) (Type I protein geranyl-geranyltransferase subunit alpha) (GGTase-I-alpha) Q04631 (A C E G I K)
Geranylgeranyl transferase type-1 subunit beta (EC 2.5.1.59) (Geranylgeranyl transferase type I subunit beta) (GGTase-I-beta) (Type I protein geranyl-geranyltransferase subunit beta) P53610 (B D F H J L)
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A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R
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1d8d, 1fpp, 1qbq, 1ft1, 1kzo, 1kzp, 1dce, 1n4p, 1n4q, 1n4r
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| A, C, E, G, I, K |
protein farnesyltransferase alpha subunit |
Protein |
Q04631 (FNTA_RAT)
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377 |
83% |
| B, D, F, H, J, L |
geranyltransferase type-I beta subunit |
Protein |
P53610 (PGTB1_RAT)
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377 |
91% |
| M, N, O, P, Q, R |
Fusion protein consisting of transforming protein p21b and Ras related protein Rap-2b |
Protein |
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11 |
45% |
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| B, D, F, H, J, L |
ZINC ION |
ZN
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| B, C, D, F, G, H, J, K, L |
CHLORIDE ION |
CL
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| B, D, F, H, J, L |
GERANYLGERANYL DIPHOSPHATE |
GRG
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| M, N, O, P, Q, R |
GERAN-8-YL GERAN |
GER
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