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EBI PDBe PDBeView

PDBe Entry: 1n4k view

Crystal structure of the inositol 1,4,5-trisphosphate receptor binding core in complex with IP3
Summary
Header MEMBRANE PROTEINsearch
Method X-RAY DIFFRACTION
Experiment Resolution: 2.2 Å, R-factor: 22.4%, Free R-factor: 24.8%, Spacegroup: C 2 2 21
Released 25/12/2002, deposition: 31/10/2002, last revision: 24/02/2009
Authors Bosanac, I.search; Alattia, J.R.search; Mal, T.K.search; Chan, J.search; Talarico, S.search; Tong, F.K.search; Tong, K.I.search; Yoshikawa, F.search; Furuichi, T.search; Iwai, M.search; Michikawa, T.search; Mikoshiba, K.search; Ikura, M.search
Primary citation Structure of the inositol 1,4,5-trisphosphate receptor binding core in complex with its ligand.
NATUREsearch vol:420, pag:696-700 (2002) [PubMed ID 12442173 ]search
Keywords IP3 RECEPTORsearch, IP3-BINDING COREsearch, CALCIUM CHANNELsearch, PROTEIN-LIGAND COMPLEXsearch, B-TREFOIL FOLDsearch, ARMADILLO-LIKE FOLDsearch, MEMBRANE PROTEINsearch
Organism Mus musculus(house mouse) 10090search(A)
UniProt Inositol 1,4,5-trisphosphate receptor type 1 (Type 1 inositol 1,4,5-trisphosphate receptor) (Type 1 InsP3 receptor) (IP3 receptor isoform 1) (InsP3R1) (Inositol 1,4,5-trisphosphate-binding protein P400) (Purkinje cell protein 1) (Protein PCD-6) P11881search (A)
Solvent A
Polymers
Id Name Type UniProt Residues Observed
A Inositol 1,4,5-trisphosphate receptor type 1 Protein P11881 (ITPR1_MOUSE)search
 381 76%
Heterogens
Id Name Ligands
A D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE I3P search
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