› 1n4e

X-ray diffraction
2.5Å resolution

Crystal Structure of a DNA Decamer Containing a Thymine-dimer

Released:
DOI: 10.2210/pdb1n4e/pdb
PDB entry 1n4e coloured by chain, front view.
PDB entry 1n4e coloured by chain, side view.
PDB entry 1n4e coloured by chain, top view.
Source organism: Synthetic construct
Primary publication:
Crystal structure of a DNA decamer containing a cis-syn thymine dimer.
Park H, Zhang K, Ren Y, Nadji S, Sinha N, Taylor JS, Kang C
Proc Natl Acad Sci U S A 99 15965-70 (2002)
PMID: 12456887

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-114230 (preferred)
Entry contents:
2 distinct DNA molecules
Macromolecules (2 distinct):
5'-D(*GP*CP*TP*TP*AP*AP*TP*TP*CP*G)-3' Chains: A, C
Molecule details ›
Chains: A, C
Length: 10 nucleotides
Theoretical weight: 3.04 KDa
Source organism: Synthetic construct
Expression system: Not provided
5'-D(*CP*GP*AP*AP*TP*TP*AP*AP*GP*C)-3' Chains: B, D
Molecule details ›
Chains: B, D
Length: 10 nucleotides
Theoretical weight: 3.05 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: P212121
Unit cell:
a: 21.11Å b: 54.01Å c: 74.19Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.197 0.197 0.255
Expression system: Not provided

Quick links

Citations

22 review citations

Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints.
Sancar et al. (2004)
21 more

6 mentions without citation

Expanding molecular roles of UV-DDB: Shining light on genome stability and cancer.
Beecher et al. (2020)
5 more