› 1n11

X-ray diffraction
2.7Å resolution

D34 REGION OF HUMAN ANKYRIN-R AND LINKER

Released:
DOI: 10.2210/pdb1n11/pdb
PDB entry 1n11 coloured by chain, front view.
PDB entry 1n11 coloured by chain, side view.
PDB entry 1n11 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structure of a 12 ANK repeat stack from human ankyrinR.
Michaely P, Tomchick DR, Machius M, Anderson RG
EMBO J 21 6387-96 (2002)
PMID: 12456646

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-147654 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ankyrin-1 Chain: A
Molecule details ›
Chain: A
Length: 437 amino acids
Theoretical weight: 46.46 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P16157 (Residues: 401-827; Coverage: 23%)
Gene names: ANK, ANK1
Sequence domains: Ankyrin repeat
Structure domains: Ankyrin repeat-containing domain

Ligands and Environments

2 bound ligands:
Ligand BR 1 x BR
Ligand CL 9 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P6322
Unit cell:
a: 137.329Å b: 137.329Å c: 197.801Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.318 0.319 0.303
Expression system: Escherichia coli

Quick links

Citations

29 review citations

Phospholipase A2 enzymes: physical structure, biological function, disease implication, chemical inhibition, and therapeutic intervention.
Dennis et al. (2011)
28 more

49 mentions without citation

Molecular mechanism of TRP channels.
Zheng J. (2013)
48 more