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NMR STRUCTURE OF THE TUMOR SUPPRESSOR BIN1: ALTERNATIVE SPLICING IN MELANOMA AND INTERACTION WITH C-MYC

Solution NMR
PDB entry 1muz coloured by chain, ensemble of 20 models, front view.
PDB entry 1muz coloured by chain, ensemble of 20 models, side view.
PDB entry 1muz coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Myc box-dependent-interacting protein 1
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Multimeric state: monomeric
PDBe Complex ID: PDB-CPX-126320

Macromolecules

Myc box-dependent-interacting protein 1
Chain: A
Length: 81 amino acids
Theoretical weight: 9.36 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O00499 (Residues: 513-593; Coverage: 14%)
Gene names: AMPHL, BIN1
Pfam: Variant SH3 domain
InterPro:
CATH: SH3 Domains
SCOP: SH3-domain
Myc box-dependent-interacting protein 1 in PDB entry 1muz, assembly 1, front view.
Myc box-dependent-interacting protein 1 in PDB entry 1muz, assembly 1, side view.
Myc box-dependent-interacting protein 1 in PDB entry 1muz, assembly 1, top view.
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