› 1muw

X-ray diffraction
0.86Å resolution

The 0.86 Angstrom Structure of Xylose Isomerase

Released:
DOI: 10.2210/pdb1muw/pdb
PDB entry 1muw coloured by chain, front view.
PDB entry 1muw coloured by chain, side view.
PDB entry 1muw coloured by chain, top view.
Source organism: Streptomyces olivochromogenes
Entry authors: Fenn TD, Ringe D, Petsko GA

Function and Biology Details

Reaction catalysed: 
Alpha-D-xylopyranose = alpha-D-xylufuranose
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo tetramer
Assembly name:
PDBe Complex ID:
PDB-CPX-147410 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Xylose isomerase Chain: A
Molecule details ›
Chain: A
Length: 386 amino acids
Theoretical weight: 42.86 KDa
Source organism: Streptomyces olivochromogenes
Expression system: Escherichia coli
UniProt:
  • Canonical: P15587 (Residues: 2-387; Coverage: 100%)
Gene name: xylA
Sequence domains: Xylose isomerase-like TIM barrel
Structure domains: Divalent-metal-dependent TIM barrel enzymes

Ligands and Environments

3 bound ligands:
Ligand MN 2 x MN
Ligand MG 2 x MG
Ligand OH 1 x OH
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: I222
Unit cell:
a: 85.906Å b: 92.883Å c: 98.321Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.126 0.124 0.143
Expression system: Escherichia coli

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