› 1muq

X-ray diffraction
2.3Å resolution

X-ray Crystal Structure of Rattlesnake Venom Complexed With Thiodigalactoside

Released:
DOI: 10.2210/pdb1muq/pdb
PDB entry 1muq coloured by chain, front view.
PDB entry 1muq coloured by chain, side view.
PDB entry 1muq coloured by chain, top view.
Source organism: Crotalus atrox
Primary publication:
X-ray crystal structure of a galactose-specific C-type lectin possessing a novel decameric quaternary structure.
Walker JR, Nagar B, Young NM, Hirama T, Rini JM
Biochemistry 43 3783-92 (2004)
PMID: 15049685

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assemblies composition:
homo decamer
homo pentamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-149485 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
C-type lectin Cal Chains: A, B, C, D, E
Molecule details ›
Chains: A, B, C, D, E
Length: 135 amino acids
Theoretical weight: 16.31 KDa
Source organism: Crotalus atrox
UniProt:
  • Canonical: P21963 (Residues: 1-135; Coverage: 100%)
Sequence domains: Lectin C-type domain
Structure domains: Mannose-Binding Protein A, subunit A

Ligands and Environments

Carbohydrate polymer : NEW Components: GAL, YIO
Ligand GAL 1 x GAL
Ligand YIO 1 x YIO
3 bound ligands:
Ligand CA 5 x CA
Ligand NA 5 x NA
Ligand GAL 3 x GAL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE A1
Spacegroup: C2221
Unit cell:
a: 110.454Å b: 151.234Å c: 95.014Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.21 0.21 0.257

Quick links

Citations

6 review citations

The C-type lectin-like domain superfamily.
Zelensky et al. (2005)
5 more

2 mentions without citation

Automated identification of protein-ligand interaction features using Inductive Logic Programming: a hexose binding case study.
A Santos et al. (2012)
1 more