› 1mmn

X-ray diffraction
2.1Å resolution

X-RAY STRUCTURES OF THE MGADP, MGATPGAMMAS, AND MGAMPPNP COMPLEXES OF THE DICTYOSTELIUM DISCOIDEUM MYOSIN MOTOR DOMAIN

Released:
DOI: 10.2210/pdb1mmn/pdb
PDB entry 1mmn coloured by chain, front view.
PDB entry 1mmn coloured by chain, side view.
PDB entry 1mmn coloured by chain, top view.
Source organism: Dictyostelium discoideum
Primary publication:
X-ray structures of the MgADP, MgATPgammaS, and MgAMPPNP complexes of the Dictyostelium discoideum myosin motor domain.
Gulick AM, Bauer CB, Thoden JB, Rayment I
Biochemistry 36 11619-28 (1997)
PMID: 9305951

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-140379 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Myosin-2 heavy chain Chain: A
Molecule details ›
Chain: A
Length: 762 amino acids
Theoretical weight: 86.78 KDa
Source organism: Dictyostelium discoideum
Expression system: Dictyostelium discoideum
UniProt:
  • Canonical: P08799 (Residues: 1-759; Coverage: 36%)
Gene names: DDB_G0286355, mhcA
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:
Ligand MG 1 x MG
Ligand ANP 1 x ANP
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE F1
Spacegroup: P21212
Unit cell:
a: 103.9Å b: 180.1Å c: 54.1Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.198 0.198 not available
Expression system: Dictyostelium discoideum

Quick links

Citations

15 review citations

Structural mechanism of muscle contraction.
Geeves et al. (1999)
14 more

5 mentions without citation

Probing the local dynamics of nucleotide-binding pocket coupled to the global dynamics: myosin versus kinesin.
Zheng et al. (2005)
4 more