› 1mij

X-ray diffraction
2.05Å resolution

Crystal Structure of the Homeo-prospero Domain of D. melanogaster Prospero

Released:
DOI: 10.2210/pdb1mij/pdb
PDB entry 1mij coloured by chain, front view.
PDB entry 1mij coloured by chain, side view.
PDB entry 1mij coloured by chain, top view.
Source organism: Drosophila melanogaster
Primary publication:
Structure of the DNA binding region of prospero reveals a novel homeo-prospero domain.
Ryter JM, Doe CQ, Matthews BW
Structure 10 1541-9 (2002)
PMID: 12429095

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-151556 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Homeobox protein prospero Chain: A
Molecule details ›
Chain: A
Length: 152 amino acids
Theoretical weight: 18.45 KDa
Source organism: Drosophila melanogaster
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P29617 (Residues: 1545-1696; Coverage: 9%)
Gene names: CG17228, pros
Sequence domains: Homeo-prospero domain
Structure domains: Homeo-prospero domain

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 5 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.2
Spacegroup: P21
Unit cell:
a: 35.3Å b: 49.9Å c: 51.5Å
α: 90° β: 97.4° γ: 90°
R-values:
R R work R free
0.216 0.216 0.256
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

6 review citations

Stem cells and retinal repair.
Klassen et al. (2004)
5 more

5 mentions without citation

Dual roles for Prox1 in the regulation of the chicken betaB1-crystallin promoter.
Chen et al. (2008)
4 more