1mh4 Summary


maltose binding-a1 homeodomain protein chimera, crystal form II

The structure was published by Ke, A. and Wolberger, C., in 2003 in a paper entitled "Insights into binding cooperativity of MATa1/MATalpha2 from the crystal structure of a MATa1 homeodomain-maltose binding protein chimera" (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.3 Å and deposited in 2002.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of maltose binding-a1 homeodomain protein chimera. This molecule has the UniProt identifier P0AEX9 (MALE_ECOLI)search. The sample contained 421 residues which is 99% of the natural sequence. Out of 421 residues 412 were observed and are deposited in the PDB.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A maltose binding-a1 homeodomain protein chimera P0AEX9 (27-392) (MALE_ECOLI)search ,
P0CY10 (77-126) (MATA1_YEASX)search
Escherichia coli K-12search ,
Saccharomyces cerevisiaesearch
96% ,
< 90%
421 99%

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (P0AEX9) Phosphate binding protein-likesearch Periplasmic binding protein-like IIsearch PF01547: Bacterial extracellular solute-binding proteinsearch

Chain ID Molecular function (GO) Biological process (GO) Cellular component (GO)
A (P0AEX9P0CY10) DNA bindingsearch maltose transmembrane transporter activitysearch protein bindingsearch sequence-specific DNA bindingsearch transporter activitysearch maltose bindingsearch transportsearch maltose transportsearch carbohydrate transportsearch detection of maltose stimulussearch maltodextrin transportsearch regulation of transcription, DNA-templatedsearch cellular response to DNA damage stimulussearch cell chemotaxissearch ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containingsearch periplasmic spacesearch outer membrane-bounded periplasmic spacesearch maltose transport complexsearch ATP-binding cassette (ABC) transporter complexsearch

Chain InterPro annotation
A Homeobox domainsearch Solute-binding family 1search Maltose binding proteinsearch Solute-binding family 1, conserved sitesearch Homeodomain-likesearch Homeobox, conserved sitesearch