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PDBe Entry: 1me7 
Inosine Monophosphate Dehydrogenase (IMPDH) From Tritrichomonas Foetus with RVP and MOA bound
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OXIDOREDUCTASE
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X-RAY DIFFRACTION
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Resolution: 2.15 Å, R-factor: 23.3%, Free R-factor: 26.4%, Spacegroup: P 4 3 2
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14/01/2003, deposition: 08/08/2002, last revision: 24/02/2009
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Prosise, G.L.; Wu, J.; Luecke, H.
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Crystal Structure of Tritrichomonas foetus Inosine Monophosphate Dehydrogenase
in Complex with the Inhibitor Ribavirin Monophosphate Reveals a Catalysis-dependent
Ion-binding Site
J.BIOL.CHEM. vol:277, pag:50654-50659 (2002) [PubMed ID 12235158 ]
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alpha beta barrel, OXIDOREDUCTASE
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1.1.1.205 ExPASy BRENDA (A)
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Tritrichomonas foetus 5724(A)
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Inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205) (IMP dehydrogenase) (IMPDH) (IMPD) P50097 (A)
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A
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1ak5, 1me8, 1me9, 1meh, 1mei, 1mew
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| A |
INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE |
Protein |
P50097 (IMDH_TRIFO)
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503 |
72% |
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| A |
SODIUM ION |
NA
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| A |
POTASSIUM ION |
K
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| A |
RIBAVIRIN MONOPHOSPHATE |
RVP
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| A |
MYCOPHENOLIC ACID |
MOA
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