1mb9 Summary

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BETA-LACTAM SYNTHETASE COMPLEXED WITH ATP

The structure was published by Miller, M.T., Bachmann, B.O., Townsend, C.A., and Rosenzweig, A.C., in 2002 in a paper entitled "The catalytic cycle of beta -lactam synthetase observed by x-ray crystallographic snapshots" (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.11 Å and deposited in 2002.

The experimental data on which the structure is based was also deposited.

This PDB entry contains multiple copies of the structure of BETA-LACTAM SYNTHETASE.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A BETA-LACTAM SYNTHETASE P0DJQ7 (1-513) (BLS_STRCL)search Streptomyces clavuligerussearch 100% 513 96%
B BETA-LACTAM SYNTHETASE P0DJQ7 (1-513) (BLS_STRCL)search Streptomyces clavuligerussearch 100% 513 96%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P0DJQ7 (1 - 513) BETA-LACTAM SYNTHETASE Streptomyces clavuligerus

Chain Structural classification (SCOP) Structural classification (CATH)
A, B (P0DJQ7) N-type ATP pyrophosphatasessearch, Class II glutamine amidotransferasessearch Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1search, HUPssearch

Chain ID Molecular function (GO) Biological process (GO)
A, B (P0DJQ7) ATP bindingsearch (carboxyethyl)arginine beta-lactam-synthase activitysearch nucleotide bindingsearch asparagine synthase (glutamine-hydrolyzing) activitysearch metal ion bindingsearch ligase activitysearch asparagine biosynthetic processsearch metabolic processsearch clavulanic acid biosynthetic processsearch

Chain InterPro annotation
A, B Class II glutamine amidotransferase domainsearch Asparagine synthasesearch Rossmann-like alpha/beta/alpha sandwich foldsearch Nucleophile aminohydrolases, N-terminalsearch