spacer
EBI PDBe PDBeView

PDBe Entry: 1mb2 view

Crystal Structure of Tryptophanyl-tRNA Synthetase Complexed with Tryptophan in an Open Conformation
Summary
Header LIGASEsearch
Method X-RAY DIFFRACTION
Experiment Resolution: 2.7 Å, R-factor: 22.0%, Free R-factor: 25.4%, Spacegroup: C 1 2 1
Released 07/01/2003, deposition: 02/08/2002, last revision: 24/02/2009
Authors Retailleau, P.search; Huang, X.search; Yin, Y.search; Hu, M.search; Weinreb, V.search; Vachette, P.search; Vonrhein, C.search; Bricogne, G.search; Roversi, P.search; Ilyin, V.search; Carter Jr., C.W.search
Primary citation Interconversion of ATP binding and conformational free energies by tryptophanyl-tRNA synthetase: structures of ATP bound to open and closed, pre-transition-state conformations.
J.MOL.BIOL.search vol:325, pag:39-63 (2003) [PubMed ID 12473451 ]search
Keywords Aminoacyl-tRNA Synthetasesearch, Rossmann foldsearch, amino acid binding sitesearch, LIGASEsearch
EC 6.1.1.2 ExPASy BRENDA search (A B C D E F)
Organism Geobacillus stearothermophilus 1422search(A B C D E F)
UniProt Tryptophanyl-tRNA synthetase (EC 6.1.1.2) (Tryptophan--tRNA ligase) (TrpRS) P00953search (A B C D E F)
Related entries 1d2r, 1i6m, 1m83, 1mau, 1maw
Polymers
Id Name Type UniProt Residues Observed
A, B, C, D, E, F TRYPTOPHAN-TRNA LIGASE Protein P00953 (SYW_BACST)search
 328 99%
Heterogens
Id Name Ligands
A, B, C, D, E, F TRYPTOPHAN TRP search
spacer