› 1m9i

X-ray diffraction
2.65Å resolution

Crystal Structure Of Phosphorylation-Mimicking Mutant T356D Of Annexin VI

Released:
DOI: 10.2210/pdb1m9i/pdb
PDB entry 1m9i coloured by chain, front view.
PDB entry 1m9i coloured by chain, side view.
PDB entry 1m9i coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structural and dynamic changes in human annexin VI induced by a phosphorylation-mimicking mutation, T356D.
Freye-Minks C, Kretsinger RH, Creutz CE
Biochemistry 42 620-30 (2003)
PMID: 12534274

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-139923 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Annexin A6 Chain: A
Molecule details ›
Chain: A
Length: 672 amino acids
Theoretical weight: 75.85 KDa
Source organism: Homo sapiens
Expression system: Saccharomyces cerevisiae
UniProt:
  • Canonical: P08133 (Residues: 2-673; Coverage: 100%)
Gene names: ANX6, ANXA6
Sequence domains: Annexin
Structure domains: Annexin

Ligands and Environments

1 bound ligand:
Ligand CA 5 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X4A
Spacegroup: P43
Unit cell:
a: 67.97Å b: 67.97Å c: 204.6Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.243 0.225 0.279
Expression system: Saccharomyces cerevisiae

Quick links

Citations

4 review citations

Annexins: linking Ca2+ signalling to membrane dynamics.
Gerke et al. (2005)
3 more

3 mentions without citation

Zooming into the Dark Side of Human Annexin-S100 Complexes: Dynamic Alliance of Flexible Partners.
Weisz et al. (2020)
2 more