› › Structure analysis

X-ray crystal structure of Cyclophilin A/HIV-1 CA N-terminal domain (1-146) M-type H87A Complex.

X-ray diffraction
1.72Å resolution
PDB entry 1m9e coloured by chain, front view.
PDB entry 1m9e coloured by chain, side view.
PDB entry 1m9e coloured by chain, top view.
Source organisms:
Assembly composition:
hetero dimer (preferred)
Entry contents: 2 distinct polypeptide molecules

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Assembly Name: Peptidyl-prolyl cis-trans isomerase A and Gag Polyprotein
hide full assembly name
Multimeric state: hetero dimer
Accessible surface area: 14626.54 Å2
Buried surface area: 794.64 Å2
Dissociation area: 397.32 Å2
Dissociation energy (ΔGdiss): -3.53 kcal/mol
Dissociation entropy (TΔSdiss): 11.2 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-158799
Assembly 2
Download    3D Visualisation
Assembly Name: Peptidyl-prolyl cis-trans isomerase A and Gag Polyprotein
hide full assembly name
Multimeric state: hetero dimer
Accessible surface area: 14736.83 Å2
Buried surface area: 1091.48 Å2
Dissociation area: 545.74 Å2
Dissociation energy (ΔGdiss): -4.96 kcal/mol
Dissociation entropy (TΔSdiss): 11.33 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-158799

Macromolecules

Peptidyl-prolyl cis-trans isomerase A
Chains: A, B
Length: 164 amino acids
Theoretical weight: 17.91 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P62937 (Residues: 1-164; Coverage: 99%)
Gene names: CYPA, PPIA
Pfam: Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
InterPro:
CATH: Cyclophilin-like
SCOP: Cyclophilin (peptidylprolyl isomerase)
Peptidyl-prolyl cis-trans isomerase A in PDB entry 1m9e, assembly 1, front view.
Peptidyl-prolyl cis-trans isomerase A in PDB entry 1m9e, assembly 1, side view.
Peptidyl-prolyl cis-trans isomerase A in PDB entry 1m9e, assembly 1, top view.
Molecule details ›

Search similar proteins

HIV-1 Capsid
Chains: C, D
Length: 146 amino acids
Theoretical weight: 16.14 KDa
Source organism: Human immunodeficiency virus 1
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q72497 (Residues: 133-278; Coverage: 29%)
Gene name: gag
Pfam: gag protein p24 N-terminal domain
InterPro:
CATH: Human Immunodeficiency Virus Type 1 Capsid Protein
SCOP: Retrovirus capsid protein, N-terminal core domain
HIV-1 Capsid in PDB entry 1m9e, assembly 1, front view.
HIV-1 Capsid in PDB entry 1m9e, assembly 1, side view.
HIV-1 Capsid in PDB entry 1m9e, assembly 1, top view.
Molecule details ›

Search similar proteins

Quick links