Function and Biology Details
Reaction catalysed:
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Biochemical function:
- not assigned
Biological process:
Cellular component:
Sequence domains:
Structure domains:
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-130107 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
SH2 domain-containing protein 1A
Molecule details ›
Chain: A
Length: 104 amino acids
Theoretical weight: 11.7 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: SH2 domain
Structure domains: SH2 domain
Length: 104 amino acids
Theoretical weight: 11.7 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
O60880 (Residues: 1-104; Coverage: 81%)
Sequence domains: SH2 domain
Structure domains: SH2 domain
Signaling lymphocytic activation molecule
Molecule details ›
Chain: B
Length: 11 amino acids
Theoretical weight: 1.28 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
Length: 11 amino acids
Theoretical weight: 1.28 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
- Canonical: Q13291 (Residues: 276-286; Coverage: 4%)
Tyrosine-protein kinase Fyn
Molecule details ›
Chain: C
Length: 61 amino acids
Theoretical weight: 6.94 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: SH3 domain
Structure domains: SH3 Domains
Length: 61 amino acids
Theoretical weight: 6.94 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: P06241 (Residues: 84-144; Coverage: 11%)
Sequence domains: SH3 domain
Structure domains: SH3 Domains
