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PDBe Entry: 1lxm view

Crystal Structure of Streptococcus agalactiae Hyaluronate Lyase Complexed with Hexasaccharide Unit of Hyaluronan
Summary
Header LYASEsearch
Method X-RAY DIFFRACTION
Experiment Resolution: 2.2 Å, R-factor: 21.8%, Free R-factor: 27.1%, Spacegroup: C 2 2 21
Released 30/10/2002, deposition: 05/06/2002, last revision: 24/02/2009
Authors Mello, L.V.search; de Groot, B.L.search; Li, S.search; Jedrzejas, M.J.search
Primary citation Structure and flexibility of Streptococcus agalactiae hyaluronate lyase complex with its substrate. Insights into the mechanism of processive degradation of hyaluronan.
J.BIOL.CHEM.search vol:277, pag:36678-36688 (2002) [PubMed ID 12130645 ]search
Keywords Streptococcus agalactiaesearch, Protein-carbohydrate complexsearch, hyaluronansearch, LYASEsearch
EC 4.2.2.1 ExPASy BRENDA search (A)
Organism Streptococcus agalactiae 1311search(A)
UniProt Hyaluronate lyase precursor (EC 4.2.2.1) (Hyaluronidase) (HYase) Q53591search (A)
Solvent A
Related entries 1f1s, 1i8q
Polymers
Id Name Type UniProt Residues Observed
A HYALURONATE Lyase Protein Q53591 (HYSA_STRA3)search
814 97%
Heterogens
Id Name Ligands
A SUGAR (NAG-GCU-NAG-GCU-NAG-GCU) NAG search BDP search
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