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PDBe Entry: 1lxc 
Crystal Structure of E. Coli Enoyl Reductase-NAD+ with a Bound Acrylamide Inhibitor
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OXIDOREDUCTASE
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X-RAY DIFFRACTION
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Resolution: 2.4 Å, R-factor: 19.9%, Free R-factor: 25.3%, Spacegroup: P 61 2 2
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04/09/2002, deposition: 05/06/2002, last revision: 24/02/2009
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Miller, W.H.; Seefeld, M.A.; Newlander, K.A.; Uzinskas, I.N.; Burgess, W.J.; Heerding, D.A.; Yuan, C.C.K.; Head, M.S.; Payne, D.J.; Rittenhouse, S.F.; Moore, T.D.; Pearson, S.C.; Dewolf, V.; Berry, W.E.; Keller, P.M.; Polizzi, B.J.; Qiu, X.; Janson, C.A.; Huffman, W.F.
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Discovery of aminopyridine-based inhibitors of bacterial enoyl-ACP reductase (FabI).
J.MED.CHEM. vol:45, pag:3246-3256 (2002) [PubMed ID 12109908 ]
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FABI, ENOYL REDUCTASE, OXIDOREDUCTASE
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1.3.1.9 ExPASy BRENDA (A B)
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Escherichia coli 562(A B)
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Enoyl-[acyl-carrier-protein] reductase [NADH] (EC 1.3.1.9) (NADH-dependent enoyl-ACP reductase) P0AEK4 (A B)
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A, B
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1c14, 1i2z, 1i30, 1qg6, 1lx6
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| A, B |
ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NADH] |
Protein |
P0AEK4 (FABI_ECOLI)
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262 |
95% |
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| A, B |
NICOTINAMIDE-ADENINE-DINUCLEOTIDE |
NAD
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| A, B |
3-(6-AMINOPYRIDIN-3-YL)-N-METHYL-N-[(1-METHYL-1H-INDOL-2-YL)METHYL]ACRYLAMIDE |
AYM
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