1lxa Summary



The structure was published by Raetz, C.R. and Roderick, S.L., in 1995 in a paper entitled "A left-handed parallel beta helix in the structure of UDP-N-acetylglucosamine acyltransferase." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.6 Å and deposited in 1995.

The experimental data on which the structure is based was not deposited.

The PDB entry contains the structure of UDP N-ACETYLGLUCOSAMINE O-ACYLTRANSFERASE. This molecule has the UniProt identifier P0A722 (LPXA_ECOLI)search. The sample contained 262 residues which is 100% of the natural sequence. Out of 262 residues 261 were observed and are deposited in the PDB.

The molecule most likely forms homotrimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A UDP N-ACETYLGLUCOSAMINE O-ACYLTRANSFERASE P0A722 (1-262) (LPXA_ECOLI)search Escherichia coli K-12search 100% 262 100%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (P0A722) UDP N-acetylglucosamine acyltransferasesearch Hexapeptide repeat proteinssearch, Udp N-acetylglucosamine O-acyltransferase; Domain 2search PF00132: Bacterial transferase hexapeptide (six repeats)search, PF13720: Udp N-acetylglucosamine O-acyltransferase; Domain 2search

Chain ID Molecular function (GO) Biological process (GO) Cellular component (GO)
A (P0A722) acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activitysearch transferase activitysearch identical protein bindingsearch transferase activity, transferring acyl groupssearch lipid biosynthetic processsearch lipid metabolic processsearch lipid A biosynthetic processsearch cytoplasmsearch

Chain InterPro annotation
A Bacterial transferase hexapeptide repeatsearch Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferasesearch Trimeric LpxA-likesearch Hexapeptide transferase, conserved sitesearch Udp N-acetylglucosamine O-acyltransferase, C-terminalsearch