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Solution NMR

Solution NMR Structure of Zinc Finger Protein yacG from Escherichia coli. Northeast Structural Genomics Consortium Target ET92.

Released:
DOI: 10.2210/pdb1lv3/pdb
PDB entry 1lv3 coloured by chain, ensemble of 20 models, front view.
PDB entry 1lv3 coloured by chain, ensemble of 20 models, side view.
PDB entry 1lv3 coloured by chain, ensemble of 20 models, top view.
Source organism: Escherichia coli
Primary publication:
NMR structure of the Escherichia coli protein YacG: a novel sequence motif in the zinc-finger family of proteins.
Ramelot TA, Cort JR, Yee AA, Semesi A, Edwards AM, Arrowsmith CH, Kennedy MA
Proteins 49 289-93 (2002)
PMID: 12211008

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-141699 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DNA gyrase inhibitor YacG Chain: A
Molecule details ›
Chain: A
Length: 68 amino acids
Theoretical weight: 7.6 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P0A8H8 (Residues: 1-65; Coverage: 100%)
Gene names: JW5008, b0101, yacG
Sequence domains: DNA gyrase inhibitor YacG
Structure domains: Erythroid Transcription Factor GATA-1, subunit A

Ligands and Environments

1 bound ligand:
Ligand ZN 1 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 90%
Refinement method: distance geometry and simulated annealing
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

2 review citations

Exploiting bacterial DNA gyrase as a drug target: current state and perspectives.
Collin et al. (2011)
1 more

5 mentions without citation

Structural classification of zinc fingers: survey and summary.
Krishna et al. (2003)
4 more