1ltq Summary



The structure was published by Galburt, E.A., Pelletier, J., Wilson, G., and Stoddard, B.L., in 2002 in a paper entitled "Structure of a tRNA repair enzyme and molecular biology workhorse: T4 polynucleotide kinase." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.33 Å and deposited in 2002.

The experimental data on which the structure is based was not deposited.

The PDB entry contains the structure of POLYNUCLEOTIDE KINASE. This molecule has the UniProt identifier P06855 (KIPN_BPT4)search. The sample contained 301 residues which is 100% of the natural sequence. Out of 301 residues 292 were observed and are deposited in the PDB.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms homotetramers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A POLYNUCLEOTIDE KINASE P06855 (1-301) (KIPN_BPT4)search Enterobacteria phage T4search 100% 301 99%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P06855 (1 - 301) POLYNUCLEOTIDE KINASE Enterobacteria phage T4

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (P06855) phosphatase domain of polynucleotide kinasesearch, Nucleotide and nucleoside kinasessearch P-loop containing nucleotide triphosphate hydrolasessearch, Rossmann foldsearch PF13671: AAA domainsearch

Chain ID Biological process (GO) Molecular function (GO)
A (P06855) cellular response to DNA damage stimulussearch phosphorylationsearch DNA repairsearch kinase activitysearch ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activitysearch nucleotide bindingsearch transferase activitysearch ATP bindingsearch

Chain InterPro annotation
A HAD-like domainsearch P-loop containing nucleoside triphosphate hydrolasesearch