› 1lte

X-ray diffraction
2Å resolution

STRUCTURE OF A LEGUME LECTIN WITH AN ORDERED N-LINKED CARBOHYDRATE IN COMPLEX WITH LACTOSE

Released:
DOI: 10.2210/pdb1lte/pdb
PDB entry 1lte coloured by chain, front view.
PDB entry 1lte coloured by chain, side view.
PDB entry 1lte coloured by chain, top view.
Source organism: Erythrina corallodendron
Primary publication:
Structure of a legume lectin with an ordered N-linked carbohydrate in complex with lactose.
Shaanan B, Lis H, Sharon N
Science 254 862-6 (1991)
PMID: 1948067

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-147701 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (3 distinct):
Lectin Chain: A
Molecule details ›
Chain: A
Length: 239 amino acids
Theoretical weight: 26.25 KDa
Source organism: Erythrina corallodendron
Expression system: Not provided
UniProt:
  • Canonical: P16404 (Residues: 27-265; Coverage: 94%)
Sequence domains: Legume lectin domain
Structure domains: Jelly Rolls

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA, XYL, MAN, FUC
Ligand NAG 2 x NAG
Ligand BMA 1 x BMA
Ligand XYL 1 x XYL
Ligand MAN 2 x MAN
Ligand FUC 1 x FUC
Carbohydrate polymer : NEW Components: BGC, GAL
Carbohydrate polymer
2 bound ligands:
Ligand MN 1 x MN
Ligand CA 1 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: C2
Unit cell:
a: 84.4Å b: 73.05Å c: 71.4Å
α: 90° β: 113.42° γ: 90°
R-values:
R R work R free
0.19 0.19 not available
Expression system: Not provided

Quick links

Citations

18 review citations

Protein glycosylation. Structural and functional aspects.
Lis et al. (1993)
17 more

1 mention without citation

Energetics of galactose- and glucose-aromatic amino acid interactions: implications for binding in galactose-specific proteins.
Sujatha et al. (2004)