1lml Summary

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LEISHMANOLYSIN

The structure was published by Schlagenhauf, E., Etges, R., and Metcalf, P., in 1998 in a paper entitled "The crystal structure of the Leishmania major surface proteinase leishmanolysin (gp63)." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 1.86 Å and deposited in 1997.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of LEISHMANOLYSIN. This molecule has the UniProt identifier P08148 (GP63_LEIMA)search. The sample contained 478 residues which is < 90% of the natural sequence. Out of 478 residues 465 were observed and are deposited in the PDB.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A LEISHMANOLYSIN P08148 (100-577) (GP63_LEIMA)search Leishmania majorsearch < 90% 478 97%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P08148 (100 - 577) LEISHMANOLYSIN Leishmania major

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A Leishmanolysinsearch Elastase; domain 1search, Leishmanolysin , domain 2search, Leishmanolysin domain 3search, Leishmanolysin domain 4search Leishmanolysinsearch

Chain ID Cellular component (GO) Molecular function (GO) Biological process (GO)
A (P08148) membranesearch metalloendopeptidase activitysearch cell adhesionsearch proteolysissearch

Chain InterPro annotation
A Peptidase M8, leishmanolysinsearch