› 1ljv

Solution NMR

Bovine Pancreatic Polypeptide Bound to DPC Micelles

Released:
DOI: 10.2210/pdb1ljv/pdb
PDB entry 1ljv coloured by chain, ensemble of 20 models, front view.
PDB entry 1ljv coloured by chain, ensemble of 20 models, side view.
PDB entry 1ljv coloured by chain, ensemble of 20 models, top view.
Source organism: Bos taurus
Primary publication:
Bovine pancreatic polypeptide (bPP) undergoes significant changes in conformation and dynamics upon binding to DPC micelles.
Lerch M, Gafner V, Bader R, Christen B, Folkers G, Zerbe O
J Mol Biol 322 1117-33 (2002)
PMID: 12367532

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-134173 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Pancreatic polypeptide Chain: A
Molecule details ›
Chain: A
Length: 37 amino acids
Theoretical weight: 4.23 KDa
Source organism: Bos taurus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P01302 (Residues: 30-65; Coverage: 35%)
Gene name: PPY
Sequence domains: Pancreatic hormone peptide

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing restraint energy minimization with explicit water
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

7 review citations

Protein design: toward functional metalloenzymes.
Yu et al. (2014)
6 more

5 mentions without citation

Peptide modifications differentially alter G protein-coupled receptor internalization and signaling bias.
Mäde et al. (2014)
4 more