1lij Summary


PDB entry 1lij (supersedes 1dh1)


The structure was published by Schumacher, M.A., Scott, D.M., Mathews, I.I., et al., Roos, D.S., Ullman, B., and Brennan, R.G., in 2000 in a paper entitled "Crystal structures of Toxoplasma gondii adenosine kinase reveal a novel catalytic mechanism and prodrug binding." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 1.86 Å and deposited in 2002.

The experimental data on which the structure is based was not deposited.

The PDB entry contains the structure of adenosine kinase. This molecule has the UniProt identifier Q9TVW2 (ADK_TOXGO)search. The sample contained 363 residues which is 100% of the natural sequence. Out of 363 residues 326 were observed and are deposited in the PDB.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A adenosine kinase Q9TVW2 (1-363) (ADK_TOXGO)search Toxoplasma gondiisearch 100% 363 90%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
Q9TVW2 (1 - 363) adenosine kinase Toxoplasma gondii

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (Q9TVW2) Ribokinase-likesearch UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligasesearch, Adenosine kinase, small domainsearch PF00294: pfkB family carbohydrate kinasesearch

Chain ID Biological process (GO) Molecular function (GO)
A (Q9TVW2) purine ribonucleoside salvagesearch phosphorylationsearch AMP salvagesearch adenosine kinase activitysearch phosphotransferase activity, alcohol group as acceptorsearch metal ion bindingsearch transferase activitysearch nucleotide bindingsearch kinase activitysearch ATP bindingsearch

Chain InterPro annotation
A Adenosine kinasesearch Carbohydrate/puine kinase, PfkB, conserved sitesearch Carbohydrate kinase PfkBsearch Ribokinase-likesearch