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EBI PDBe PDBeView

PDBe Entry: 1lho view

CRYSTAL STRUCTURE OF THE N-TERMINAL LG-DOMAIN OF SHBG IN COMPLEX WITH 5ALPHA-ANDROSTANE-3BETA,17BETA-DIOL
Summary
Header TRANSPORT PROTEINsearch
Method X-RAY DIFFRACTION
Experiment Resolution: 2.0 Å, R-factor: 18.7%, Free R-factor: 22.3%, Spacegroup: H 3 2
Released 23/10/2002, deposition: 17/04/2002, last revision: 24/02/2009
Authors Grishkovskaya, I.search; Avvakumov, G.V.search; Hammond, G.L.search; Catalano, M.G.search; Muller, Y.A.search
Primary citation Steroid Ligands Bind Human Sex Hormone-binding Globulin in Specific Orientations and Produce Distinct Changes in Protein Conformation
J.BIOL.CHEM.search vol:277, pag:32086-32093 (2002) [PubMed ID 12065592 ]search
Keywords SHBGsearch, 17b-DHAsearch, TRANSPORT PROTEINsearch
Organism Homo sapiens(human) 9606search(A)
UniProt Sex hormone-binding globulin precursor (SHBG) (Sex steroid-binding protein) (SBP) (Testis-specific androgen-binding protein) (ABP) (Testosterone-estrogen-binding globulin) (Testosterone-estradiol-binding globulin) (TeBG) P04278search (A)
Solvent A
Related entries 1d2s, 1f5f, 1kdk, 1kdm, 1lhn, 1lhu, 1lhv, 1lhw
Polymers
Id Name Type UniProt Residues Observed
A SEX HORMONE-BINDING GLOBULIN Protein P04278 (SHBG_HUMAN)search
 189 93%
Heterogens
Id Name Ligands
A CALCIUM ION CA search
A 5-ALPHA-ANDROSTANE-3-BETA,17BETA-DIOL AOM search
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