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EBI PDBe PDBeView

PDBe Entry: 1lbl view

Crystal structure of indole-3-glycerol phosphate synthase (IGPS) in complex with 1-(o-carboxyphenylamino)-1-deoxyribulose 5'-phosphate (CdRP)
Summary
Header LYASEsearch
Method X-RAY DIFFRACTION
Experiment Resolution: 2.4 Å, R-factor: 19.7%, Free R-factor: 24.7%, Spacegroup: P 21 21 21
Released 18/09/2002, deposition: 04/04/2002, last revision: 24/02/2009
Authors Hennig, M.search; Darimont, B.D.search; Kirschner, K.search; Jansonius, J.N.search
Primary citation The catalytic mechanism of indole-3-glycerol phosphate synthase: Crystal structures of complexes of the enzyme from Sulfolobus solfataricus with the substrate analogue, substrate, and product
J.MOL.BIOL.search vol:319, pag:757-766 (2002) [PubMed ID 12054868 ]search
Keywords BETA BARRELsearch, tryptophan biosynthesissearch, protein ligand complexsearch, substrate complexsearch, LYASEsearch
EC 4.1.1.48 ExPASy BRENDA search (A)
Organism Sulfolobus solfataricus 2287search(A)
UniProt Indole-3-glycerol phosphate synthase (EC 4.1.1.48) (IGPS) Q06121search (A)
Solvent A
Related entries 1igs, 1a53, 1lbf
Polymers
Id Name Type UniProt Residues Observed
A indole-3-glycerol phosphate synthase Protein Q06121 (TRPC_SULSO)search
 247 100%
Heterogens
Id Name Ligands
A 1-(O-CARBOXY-PHENYLAMINO)-1-DEOXY-D-RIBULOSE-5-PHOSPHATE 137 search
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