Crystal structure of R292K mutant influenza virus neuraminidase in complex with BCX-1812
The structure was published by Smith, B.J., McKimm-Breshkin, J.L., McDonald, M., Fernley, R.T., Varghese, J.N., and Colman, P.M., in 2002 in a paper entitled "Structural studies of the resistance of influenza virus neuramindase to inhibitors." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 1.85 Å and deposited in 2002.
The experimental data on which the structure is based was also deposited.
The PDB entry contains the structure of neuraminidase. This molecule has the UniProt identifier P03472 (NRAM_I75A5). The sample contained 388 residues which is < 90% of the natural sequence. Out of 388 residues 388 were observed and are deposited in the PDB.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule most likely forms homotetramers.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: