1l6o Summary

pdbe.org/1l6o
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XENOPUS DISHEVELLED PDZ DOMAIN

The structure was published by Cheyette, B.N.R., Waxman, J.S., Miller, J.R., et al., Fox, E.P., Earnest, T., and Moon, R.T., in 2002 in a paper entitled "Dapper, a Dishevelled-associated antagonist of beta-catenin and JNK signaling, is required for notochord formation" (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.2 Å and deposited in 2002.

The experimental data on which the structure is based was not deposited.

This PDB entry contains a complex of 2 biomacromolecules, namely Segment polarity protein dishevelled homolog DVL-2 and Dapper 1.

The molecule most likely forms heterohexamers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Segment polarity protein dishevelled homolog DVL-2 P51142 (252-340) (DVL2_XENLA)search Xenopus laevissearch < 90% 95 100%
B Segment polarity protein dishevelled homolog DVL-2 P51142 (252-340) (DVL2_XENLA)search Xenopus laevissearch < 90% 95 100%
C Segment polarity protein dishevelled homolog DVL-2 P51142 (252-340) (DVL2_XENLA)search Xenopus laevissearch < 90% 95 100%
D Dapper 1 Not available
Synthetic Not available 8 100%
E Dapper 1 Not available
Synthetic Not available 8 100%
F Dapper 1 Not available
Synthetic Not available 8 100%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P51142 (252 - 340) Segment polarity protein dishevelled homolog DVL-2 Xenopus laevis

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A, B, C PDZ domainsearch Pdz3 Domainsearch PDZ domain (Also known as DHR or GLGF)search
D, E, F

Chain ID Biological process (GO)
A, B, C (P51142) Wnt signaling pathwaysearch

Chain InterPro annotation
A, B, C PDZ domainsearch Dishevelled-2search Dishevelled-related proteinsearch
D, E, F