1l6g Summary


Alanine racemase bound with N-(5'-phosphopyridoxyl)-D-alanine

The structure was published by Watanabe, A., Yoshimura, T., Mikami, B., Hayashi, H., Kagamiyama, H., and Esaki, N., in 2002 in a paper entitled "Reaction mechanism of alanine racemase from Bacillus stearothermophilus: x-ray crystallographic studies of the enzyme bound with N-(5'-phosphopyridoxyl)alanine." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.0 Å and deposited in 2002.

The experimental data on which the structure is based was not deposited.

This PDB entry contains multiple copies of the structure of alanine racemase.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms homodimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A alanine racemase P10724 (1-388) (ALR_GEOSE)search Geobacillus stearothermophilussearch 98% 388 98%
B alanine racemase P10724 (1-388) (ALR_GEOSE)search Geobacillus stearothermophilussearch 98% 388 98%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P10724 (1 - 388) alanine racemase Geobacillus stearothermophilus

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A, B (P10724) Alanine racemasesearch, Alanine racemase-like, N-terminal domainsearch Alanine racemasesearch, Lyase, Ornithine Decarboxylase; Chain A, domain 1search PF00842: Alanine racemase, C-terminal domainsearch, PF01168: Alanine racemase, N-terminal domainsearch

Chain ID Molecular function (GO) Biological process (GO)
A, B (P10724) isomerase activitysearch alanine racemase activitysearch pyridoxal phosphate bindingsearch catalytic activitysearch alanine metabolic processsearch D-alanine biosynthetic processsearch

Chain InterPro annotation
A, B Alanine racemasesearch Alanine racemase, N-terminalsearch Alanine racemase/group IV decarboxylase, C-terminalsearch Alanine racemase, C-terminalsearch Alanine racemase, pyridoxal-phosphate attachment sitesearch PLP-binding barrelsearch