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EBI PDBe PDBeView

PDBe Entry: 1l4u view

CRYSTAL STRUCTURE OF SHIKIMATE KINASE FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH MGADP AND PT(II) AT 1.8 ANGSTROM RESOLUTION
Summary
Header TRANSFERASEsearch
Method X-RAY DIFFRACTION
Experiment Resolution: 1.8 Å, R-factor: 22.1%, Free R-factor: 24.9%, Spacegroup: P 32 2 1
Released 12/06/2002, deposition: 05/03/2002, last revision: 24/02/2009
Authors Gu, Y.search; Reshetnikova, L.search; Li, Y.search; Wu, Y.search; Yan, H.search; Singh, S.search; Ji, X.search
Primary citation Crystal structure of shikimate kinase from Mycobacterium tuberculosis reveals the dynamic role of the LID domain in catalysis.
J.MOL.BIOL.search vol:319, pag:779-789 (2002) [PubMed ID 12054870 ]search
Keywords SHIKIMATE PATHWAYsearch, SHIKIMATE KINASEsearch, X-RAY CRYSTALLOGRAPHYsearch, PHORSPHORYL TRANSFERsearch, DRUG DESIGNsearch, TRANSFERASEsearch
EC 2.7.1.71 ExPASy BRENDA search (A)
Organism Mycobacterium tuberculosis 1773search(A)
UniProt Shikimate kinase (EC 2.7.1.71) (SK) P0A4Z2search (A)
Solvent A
Related entries 1l4y, 1shk, 2shk, 1e6c
Polymers
Id Name Type UniProt Residues Observed
A SHIKIMATE KINASE Protein P0A4Z2 (AROK_MYCTU)search
 176 93%
Heterogens
Id Name Ligands
A PLATINUM (II) ION PT search
A MAGNESIUM ION MG search
A CHLORIDE ION CL search
A ADENOSINE-5'-DIPHOSPHATE ADP search
A 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID EPE search
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