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EBI PDBe PDBeView

PDBe Entry: 1l3r view

Crystal Structure of a Transition State Mimic of the Catalytic Subunit of cAMP-dependent Protein Kinase
Summary
Header TRANSFERASEsearch
Method X-RAY DIFFRACTION
Experiment Resolution: 2.0 Å, R-factor: 20.5%, Free R-factor: 23.2%, Spacegroup: P 21 21 21
Released 20/03/2002, deposition: 28/02/2002, last revision: 24/02/2009
Authors Madhusudansearch; Akamine, P.search; Xuong, N.-H.search; Taylor, S.S.search
Primary citation Crystal structure of a transition state mimic of the catalytic subunit of cAMP-dependent protein kinase.
NAT.STRUCT.BIOL.search vol:9, pag:273-277 (2002) [PubMed ID 11896404 ]search
Keywords protein kinasesearch, protein-ALF3 complexsearch, transition state mimicsearch, TRANSFERASEsearch
EC 2.7.11.11 ExPASy BRENDA search (E)
Organism Mus musculus(house mouse) 10090search(E)
UniProt cAMP-dependent protein kinase catalytic subunit alpha (EC 2.7.11.11) (PKA C-alpha) P05132search (E)
cAMP-dependent protein kinase inhibitor alpha (cAMP-dependent protein kinase inhibitor, muscle/brain isoform) (PKI-alpha) P63248search (I)
Solvent E, I
Related entries 1apm, 1atp, 1jbp
Polymers
Id Name Type UniProt Residues Observed
E CAMP-DEPENDENT PROTEIN KINASE, ALPHA-CATALYTIC SUBUNIT Protein P05132 (KAPCA_MOUSE)search
 350 97%
I CAMP-DEPENDENT PROTEIN KINASE INHIBITOR, MUSCLE/BRAIN FORM Protein P63248 (IPKA_MOUSE)search
 20 100%
Heterogens
Id Name Ligands
E MAGNESIUM ION MG search
E ADENOSINE-5'-DIPHOSPHATE ADP search
E ALUMINUM FLUORIDE AF3 search
E (4S)-2-METHYL-2,4-PENTANEDIOL MPD search
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