1kzh Summary

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Structure of a pyrophosphate-dependent phosphofructokinase from the Lyme disease spirochete Borrelia burgdorferi

The structure was published by Moore, S.A., Ronimus, R.S., Roberson, R.S., and Morgan, H.W., in 2002 in a paper entitled "The structure of a pyrophosphate-dependent phosphofructokinase from the Lyme disease spirochete Borrelia burgdorferi." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.55 Å and deposited in 2002.

The experimental data on which the structure is based was also deposited.

This PDB entry contains multiple copies of the structure of phosphofructokinase.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms homodimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A phosphofructokinase P70826 (1-553) (PFP_BORBU)search Borrelia burgdorferi B31search 100% 555 99%
B phosphofructokinase P70826 (1-553) (PFP_BORBU)search Borrelia burgdorferi B31search 100% 555 99%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P70826 (1 - 553) phosphofructokinase Borrelia burgdorferi

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A, B (P70826) Phosphofructokinasesearch Rossmann foldsearch, Phosphofructokinase; domain 3search PF00365: Phosphofructokinasesearch

Chain ID Biological process (GO) Molecular function (GO) Cellular component (GO)
A, B (P70826) glycolytic processsearch carbohydrate phosphorylationsearch fructose 6-phosphate metabolic processsearch phosphorylationsearch diphosphate-fructose-6-phosphate 1-phosphotransferase activitysearch 6-phosphofructokinase activitysearch metal ion bindingsearch ATP bindingsearch transferase activitysearch kinase activitysearch cytoplasmsearch

Chain InterPro annotation
A, B Phosphofructokinase domainsearch Pyrophosphate-dependent phosphofructokinase PfpBsearch Pyrophosphate-dependent phosphofructokinase, alpha-helical domainsearch Phosphofructokinasesearch