1kwb Summary

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Crystal structure of the His145Ala mutant of 2,3-dihydroxybipheny dioxygenase (BphC)

The structure was published by Sato, N., Uragami, Y., Nishizaki, T., et al., Masai, E., Fukuda, M., and Senda, T., in 2002 in a paper entitled "Crystal Structures of the Reaction Intermediate and its Homologue of an Extradiol-cleaving Catecholic Dioxygenase" (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.0 Å and deposited in 2002.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of 2,3-Dihydroxybiphenyl dioxygenase. This molecule has the UniProt identifier P17297 (BPHC_PSES1)search. The sample contained 292 residues which is 100% of the natural sequence. Out of 292 residues 288 were observed and are deposited in the PDB.

The molecule most likely forms homooctamers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
B 2,3-Dihydroxybiphenyl dioxygenase P17297 (2-293) (BPHC_PSES1)search Pseudomonas sp. KKS102search 100% 292 98%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P17297 (2 - 293) 2,3-Dihydroxybiphenyl dioxygenase Pseudomonas sp. KKS102

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
B (P17297) Extradiol dioxygenasessearch 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1search PF00903: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamilysearch

Chain ID Biological process (GO) Molecular function (GO)
B (P17297) cellular aromatic compound metabolic processsearch oxidation-reduction processsearch aromatic compound catabolic processsearch oxidoreductase activitysearch metal ion bindingsearch biphenyl-2,3-diol 1,2-dioxygenase activitysearch dioxygenase activitysearch catalytic activitysearch ferrous iron bindingsearch

Chain InterPro annotation
B Extradiol ring-cleavage dioxygenase, class I /IIsearch Glyoxalase/fosfomycin resistance/dioxygenase domainsearch Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenasesearch