spacer Crystal structure of HLA-DR1/TPI(23-37) complexed with staphylococcal enterotoxin C3 variant 3B2 (SEC3-3B2)
CATH: Protein Structure Classification
CATH code 3.10.320.10 search
Domains
1kluA01
Name Hla class ii histocompatibility antigen, dr alpha chain. Chain: a. Fragment: residues 29-207. Synonym: hla-dr1 alpha subunit. Hla-dr antigenalpha chain. Engineered: yes. Hla class ii histocompatibility antigen, dr-1 beta chain. Chain: b. Fragment: residues 30-219. Synonym: hla-dr1 beta subunit. Hla-dr beta 1 chain. Engineered: yes. Triosephosphateisomerase peptide. Chain: c. Fragment: residues 23-37. Engineered: yes. Enterotoxin type c-3. Chain: d. Fragment: residues 29-266. Synonym:enterotoxin c3. Sec3. Engineered: yes
Source Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichiacoli. Expression_system_taxid: 562. Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562. Yes. Other_details: peptide synthesis.
Polymers A
Hierarchy
Class Alpha Betasearch
Architecture Roll search
Topology Class II Histocompatibility Antigen, M Beta Chain; Chain B, domain 1 search
Homologous superfamily Class II Histocompatibility Antigen, M Beta Chain; Chain B, domain 1 search
 
CATH code 2.60.40.10 search
Domains
1kluA02
Name Hla class ii histocompatibility antigen, dr alpha chain. Chain: a. Fragment: residues 29-207. Synonym: hla-dr1 alpha subunit. Hla-dr antigenalpha chain. Engineered: yes. Hla class ii histocompatibility antigen, dr-1 beta chain. Chain: b. Fragment: residues 30-219. Synonym: hla-dr1 beta subunit. Hla-dr beta 1 chain. Engineered: yes. Triosephosphateisomerase peptide. Chain: c. Fragment: residues 23-37. Engineered: yes. Enterotoxin type c-3. Chain: d. Fragment: residues 29-266. Synonym:enterotoxin c3. Sec3. Engineered: yes
Source Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichiacoli. Expression_system_taxid: 562. Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562. Yes. Other_details: peptide synthesis.
Polymers A
Hierarchy
Class Mainly Betasearch
Architecture Sandwich search
Topology Immunoglobulin-like search
Homologous superfamily Immunoglobulins search
 
CATH code 3.10.320.10 search
Domains
1kluB01
Name Hla class ii histocompatibility antigen, dr alpha chain. Chain: a. Fragment: residues 29-207. Synonym: hla-dr1 alpha subunit. Hla-dr antigenalpha chain. Engineered: yes. Hla class ii histocompatibility antigen, dr-1 beta chain. Chain: b. Fragment: residues 30-219. Synonym: hla-dr1 beta subunit. Hla-dr beta 1 chain. Engineered: yes. Triosephosphateisomerase peptide. Chain: c. Fragment: residues 23-37. Engineered: yes. Enterotoxin type c-3. Chain: d. Fragment: residues 29-266. Synonym:enterotoxin c3. Sec3. Engineered: yes
Source Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichiacoli. Expression_system_taxid: 562. Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562. Yes. Other_details: peptide synthesis.
Polymers B
Hierarchy
Class Alpha Betasearch
Architecture Roll search
Topology Class II Histocompatibility Antigen, M Beta Chain; Chain B, domain 1 search
Homologous superfamily Class II Histocompatibility Antigen, M Beta Chain; Chain B, domain 1 search
 
CATH code 2.60.40.10 search
Domains
1kluB02
Name Hla class ii histocompatibility antigen, dr alpha chain. Chain: a. Fragment: residues 29-207. Synonym: hla-dr1 alpha subunit. Hla-dr antigenalpha chain. Engineered: yes. Hla class ii histocompatibility antigen, dr-1 beta chain. Chain: b. Fragment: residues 30-219. Synonym: hla-dr1 beta subunit. Hla-dr beta 1 chain. Engineered: yes. Triosephosphateisomerase peptide. Chain: c. Fragment: residues 23-37. Engineered: yes. Enterotoxin type c-3. Chain: d. Fragment: residues 29-266. Synonym:enterotoxin c3. Sec3. Engineered: yes
Source Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichiacoli. Expression_system_taxid: 562. Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562. Yes. Other_details: peptide synthesis.
Polymers B
Hierarchy
Class Mainly Betasearch
Architecture Sandwich search
Topology Immunoglobulin-like search
Homologous superfamily Immunoglobulins search
 
CATH code 2.40.50.110 search
Domains
1kluD01
Name Hla class ii histocompatibility antigen, dr alpha chain. Chain: a. Fragment: residues 29-207. Synonym: hla-dr1 alpha subunit. Hla-dr antigenalpha chain. Engineered: yes. Hla class ii histocompatibility antigen, dr-1 beta chain. Chain: b. Fragment: residues 30-219. Synonym: hla-dr1 beta subunit. Hla-dr beta 1 chain. Engineered: yes. Triosephosphateisomerase peptide. Chain: c. Fragment: residues 23-37. Engineered: yes. Enterotoxin type c-3. Chain: d. Fragment: residues 29-266. Synonym:enterotoxin c3. Sec3. Engineered: yes
Source Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichiacoli. Expression_system_taxid: 562. Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562. Yes. Other_details: peptide synthesis.
Polymers D
Uniprot P0A0L5
Hierarchy
Class Mainly Betasearch
Architecture Beta Barrel search
Topology OB fold (Dihydrolipoamide Acetyltransferase, E2P) search
Homologous superfamily OB fold (Dihydrolipoamide Acetyltransferase, E2P) search
 
CATH code 3.10.20.120 search
Domains
1kluD02
Name Hla class ii histocompatibility antigen, dr alpha chain. Chain: a. Fragment: residues 29-207. Synonym: hla-dr1 alpha subunit. Hla-dr antigenalpha chain. Engineered: yes. Hla class ii histocompatibility antigen, dr-1 beta chain. Chain: b. Fragment: residues 30-219. Synonym: hla-dr1 beta subunit. Hla-dr beta 1 chain. Engineered: yes. Triosephosphateisomerase peptide. Chain: c. Fragment: residues 23-37. Engineered: yes. Enterotoxin type c-3. Chain: d. Fragment: residues 29-266. Synonym:enterotoxin c3. Sec3. Engineered: yes
Source Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichiacoli. Expression_system_taxid: 562. Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562. Yes. Other_details: peptide synthesis.
Polymers D
Uniprot P0A0L5
Hierarchy
Class Alpha Betasearch
Architecture Roll search
Topology Ubiquitin-like (UB roll) search
Homologous superfamily Ubiquitin-like (UB roll) search
 
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