1kjw Summary


SH3-Guanylate Kinase Module from PSD-95

The structure was published by McGee, A.W., Dakoji, S.R., Olsen, O., Bredt, D.S., Lim, W.A., and Prehoda, K.E., in 2001 in a paper entitled "Structure of the SH3-Guanylate Kinase Module from PSD-95 Suggests a Mechanism for Regulated Assembly of MAGUK Scaffolding Proteins" (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 1.8 Å and deposited in 2001.

The experimental data on which the structure is based was not deposited.

The PDB entry contains the structure of POSTSYNAPTIC DENSITY PROTEIN 95. This molecule has the UniProt identifier P31016 (DLG4_RAT)search. The sample contained 295 residues which is < 90% of the natural sequence. Out of 295 residues 292 were observed and are deposited in the PDB.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A POSTSYNAPTIC DENSITY PROTEIN 95 P31016 (430-724) (DLG4_RAT)search Rattus norvegicussearch 100% 295 98%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P31016 (430 - 724) POSTSYNAPTIC DENSITY PROTEIN 95 Rattus norvegicus

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (P31016) SH3-domainsearch, Nucleotide and nucleoside kinasessearch SH3 Domainssearch, P-loop containing nucleotide triphosphate hydrolasessearch, Guanylate Kinase phosphate binding domainsearch PF00625: Guanylate kinasesearch, PF07653: Variant SH3 domainsearch
Chain InterPro annotation
A SH3 domainsearch Guanylate kinase-likesearch Guanylate kinase/L-type calcium channel beta subunitsearch Variant SH3 domainsearch Disks large 1search Guanylate kinase, conserved sitesearch P-loop containing nucleoside triphosphate hydrolasesearch