1khp Summary


Monoclinic form of papain/ZLFG-DAM covalent complex

The structure was published by Janowski, R., Kozak, M., Jankowska, E., Grzonka, Z., and Jaskolski, M., in 2004 in a paper entitled "Two polymorphs of a covalent complex between papain and a diazomethylketone inhibitor" (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.0 Å and deposited in 2001.

The experimental data on which the structure is based was also deposited.

This PDB entry contains a complex of 2 biomacromolecules, namely Papain and peptidic inhibitor.

The molecule most likely forms heterodimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Papain P00784 (134-345) (PAPA1_CARPA)search Carica papayasearch 98% 212 100%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P00784 (134 - 345) Papain Carica papaya

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (P00784) Papain-likesearch Cysteine proteinasessearch PF00112: Papain family cysteine proteasesearch

Chain ID Molecular function (GO) Biological process (GO)
A (P00784) cysteine-type peptidase activitysearch proteolysissearch

Chain InterPro annotation
A Cysteine peptidase, cysteine active sitesearch Peptidase C1A, papain C-terminalsearch Peptidase C1Asearch Cysteine peptidase, histidine active sitesearch Cysteine peptidase, asparagine active sitesearch