1kg0 Summary

pdbe.org/1kg0
spacer

Structure of the Epstein-Barr Virus gp42 Protein Bound to the MHC class II Receptor HLA-DR1

The structure was published by Mullen, M.M., Haan, K.M., Longnecker, R., and Jardetzky, T.S., in 2002 in a paper entitled "Structure of the Epstein-Barr virus gp42 protein bound to the MHC class II receptor HLA-DR1." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.65 Å and deposited in 2001.

The experimental data on which the structure is based was not deposited.

This entry contains 8 copies of 4 unique biopolymers (complete list).

The molecule most likely forms heterotetramers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A MHC class II Receptor HLA-DR1 P01903 (28-207) (DRA_HUMAN)search Homo sapienssearch < 90% 180 100%
B MHC class II Receptor HLA-DR1 P04229 (32-219) (2B11_HUMAN)search Homo sapienssearch < 90% 188 100%
D Hemagglutinin HA Peptide Not available
Synthetic Not available 13 100%
C gp42 Protein P03205 (86-221) (GP42_EBVB9)search Human herpesvirus 4 (strain B95-8)search < 90% 136 100%


This entry contains 3 unique UniProt proteins:

UniProt accession Name Organism PDB
P01903 (28 - 207) MHC class II Receptor HLA-DR1 Homo sapiens
P04229 (32 - 219) MHC class II Receptor HLA-DR1 Homo sapiens
P03205 (86 - 221) gp42 Protein Human herpesvirus 4

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A C1 set domains (antibody constant domain-like)search, MHC antigen-recognition domainsearch Class II Histocompatibility Antigen, M Beta Chain; Chain B, domain 1search, Immunoglobulinssearch Class II histocompatibility antigen, alpha domainsearch, Immunoglobulin C1-set domainsearch
B C1 set domains (antibody constant domain-like)search, MHC antigen-recognition domainsearch Class II Histocompatibility Antigen, M Beta Chain; Chain B, domain 1search, Immunoglobulinssearch Class II histocompatibility antigen, beta domainsearch, Immunoglobulin C1-set domainsearch
D
C C-type lectin domainsearch Mannose-Binding Protein A, subunit Asearch Lectin C-type domainsearch

Chain ID Biological process (GO) Cellular component (GO) Molecular function (GO)
A (P01903) antigen processing and presentationsearch immune responsesearch membranesearch MHC class II protein complexsearch
B (P04229) antigen processing and presentationsearch immune responsesearch MHC class II protein complexsearch membranesearch
C (P03205) carbohydrate bindingsearch

Chain InterPro annotation
A MHC class II, alpha chain, N-terminalsearch Immunoglobulin/major histocompatibility complex, conserved sitesearch Immunoglobulin C1-setsearch Immunoglobulin-like domainsearch MHC classes I/II-like antigen recognition proteinsearch Immunoglobulin-like foldsearch MHC class II, alpha/beta chain, N-terminalsearch
B MHC class II, beta chain, N-terminalsearch Immunoglobulin/major histocompatibility complex, conserved sitesearch Immunoglobulin C1-setsearch Immunoglobulin-like domainsearch MHC classes I/II-like antigen recognition proteinsearch Immunoglobulin-like foldsearch MHC class II, alpha/beta chain, N-terminalsearch
D
C C-type lectinsearch C-type lectin-likesearch C-type lectin foldsearch