› › Structure analysis

Crystal Structure of Human m-Calpain Form I

X-ray diffraction
3.15Å resolution
PDB entry 1kfx coloured by chain, front view.
PDB entry 1kfx coloured by chain, side view.
PDB entry 1kfx coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
hetero dimer (preferred)
Entry contents: 2 distinct polypeptide molecules

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Assembly Name: M-Calpain complex
hide full assembly name
Multimeric state: hetero dimer
Accessible surface area: 37771.97 Å2
Buried surface area: 5762.48 Å2
Dissociation area: 2,881.24 Å2
Dissociation energy (ΔGdiss): 31.02 kcal/mol
Dissociation entropy (TΔSdiss): 13.71 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-138096
Complex Portal ID: CPX-2674

Macromolecules

Calpain-2 catalytic subunit
Chain: L
Length: 699 amino acids
Theoretical weight: 79.97 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P17655 (Residues: 2-700; Coverage: 100%)
Gene names: CANPL2, CAPN2
Pfam:
InterPro:
CATH:
SCOP:
Calpain-2 catalytic subunit in PDB entry 1kfx, assembly 1, front view.
Calpain-2 catalytic subunit in PDB entry 1kfx, assembly 1, side view.
Calpain-2 catalytic subunit in PDB entry 1kfx, assembly 1, top view.
Molecule details ›

Search similar proteins

Calpain small subunit 1
Chain: S
Length: 184 amino acids
Theoretical weight: 21.26 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P04632 (Residues: 85-268; Coverage: 69%)
Gene names: CAPN4, CAPNS, CAPNS1
InterPro:
CATH: EF-hand
SCOP: Penta-EF-hand proteins
Calpain small subunit 1 in PDB entry 1kfx, assembly 1, front view.
Calpain small subunit 1 in PDB entry 1kfx, assembly 1, side view.
Calpain small subunit 1 in PDB entry 1kfx, assembly 1, top view.
Molecule details ›

Search similar proteins

Quick links