› 1kex

X-ray diffraction
1.9Å resolution

Crystal Structure of the b1 Domain of Human Neuropilin-1

Released:
DOI: 10.2210/pdb1kex/pdb
PDB entry 1kex coloured by chain, front view.
PDB entry 1kex coloured by chain, side view.
PDB entry 1kex coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structure of the human neuropilin-1 b1 domain.
Lee CC, Kreusch A, McMullan D, Ng K, Spraggon G
Structure 11 99-108 (2003)
PMID: 12517344

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-127136 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Neuropilin-1 Chain: A
Molecule details ›
Chain: A
Length: 155 amino acids
Theoretical weight: 17.59 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
  • Canonical: O14786 (Residues: 273-427; Coverage: 17%)
Gene names: NRP, NRP1, VEGF165R
Sequence domains: F5/8 type C domain
Structure domains: Galactose-binding domain-like

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FR-D
Spacegroup: P41212
Unit cell:
a: 62.827Å b: 62.827Å c: 88.375Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.189 0.189 0.266
Expression system: Trichoplusia ni

Quick links

Citations

16 review citations

Mammalian collagen receptors.
Leitinger et al. (2007)
15 more

15 mentions without citation

Structural basis for ligand and heparin binding to neuropilin B domains.
Vander Kooi et al. (2007)
14 more