1kd2 Summary

pdbe.org/1kd2
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Crystal Structure of Human Deoxyhemoglobin in Absence of Any Anions

A publication describing this structure is not available. The depositing authors are Colombo, M.F.search; Seixas, F.A.V.search

This crystal structure was determined using X-ray diffraction at a resolution of 1.87 Å and deposited in 2001.

The experimental data on which the structure is based was also deposited.

This PDB entry contains a complex of 2 biomacromolecules, namely Hemoglobin alpha chain and Hemoglobin beta chain.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms heterotetramers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Hemoglobin alpha chain P69905 (2-142) (HBA_HUMAN)search Homo sapienssearch 98% 141 100%
C Hemoglobin alpha chain P69905 (2-142) (HBA_HUMAN)search Homo sapienssearch 98% 141 100%
B Hemoglobin beta chain P68871 (2-147) (HBB_HUMAN)search Homo sapienssearch 98% 146 100%
D Hemoglobin beta chain P68871 (2-147) (HBB_HUMAN)search Homo sapienssearch 98% 146 100%


This entry contains 2 unique UniProt proteins:

UniProt accession Name Organism PDB
P69905 (2 - 142) Hemoglobin alpha chain Homo sapiens
P68871 (2 - 147) Hemoglobin beta chain Homo sapiens

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A, C (P69905) Globinssearch Globinssearch PF00042: Globinsearch
B, D (P68871) Globinssearch Globinssearch PF00042: Globinsearch

Chain ID Molecular function (GO) Biological process (GO) Cellular component (GO)
A, C (P69905) oxygen bindingsearch protein bindingsearch heme bindingsearch iron ion bindingsearch haptoglobin bindingsearch peroxidase activitysearch metal ion bindingsearch oxygen transporter activitysearch oxygen transportsearch bicarbonate transportsearch oxidation-reduction processsearch response to hydrogen peroxidesearch small molecule metabolic processsearch hydrogen peroxide catabolic processsearch protein heterooligomerizationsearch transportsearch positive regulation of cell deathsearch cytosolsearch hemoglobin complexsearch extracellular vesicular exosomesearch membranesearch haptoglobin-hemoglobin complexsearch extracellular regionsearch cytosolic small ribosomal subunitsearch endocytic vesicle lumensearch blood microparticlesearch
B, D (P68871) oxygen bindingsearch hemoglobin bindingsearch protein bindingsearch peroxidase activitysearch heme bindingsearch iron ion bindingsearch haptoglobin bindingsearch oxygen transporter activitysearch metal ion bindingsearch positive regulation of cell deathsearch oxidation-reduction processsearch oxygen transportsearch bicarbonate transportsearch response to hydrogen peroxidesearch renal absorptionsearch blood coagulationsearch transportsearch regulation of blood pressuresearch nitric oxide transportsearch protein heterooligomerizationsearch hydrogen peroxide catabolic processsearch platelet aggregationsearch positive regulation of nitric oxide biosynthetic processsearch small molecule metabolic processsearch regulation of blood vessel sizesearch hemoglobin complexsearch cytosolsearch extracellular vesicular exosomesearch extracellular regionsearch haptoglobin-hemoglobin complexsearch endocytic vesicle lumensearch blood microparticlesearch

Chain InterPro annotation
A, C Globinsearch Haemoglobin, alphasearch Haemoglobin, pisearch Globin-likesearch Globin, structural domainsearch
B, D Globinsearch Haemoglobin, betasearch Globin-likesearch Globin, structural domainsearch