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EBI PDBe PDBeView

PDBe Entry: 1jzs view

Isoleucyl-tRNA synthetase Complexed with mupirocin
Summary
Header LIGASEsearch
Method X-RAY DIFFRACTION
Experiment Resolution: 2.5 Å, R-factor: 24.9%, Free R-factor: 27.4%, Spacegroup: C 1 2 1
Released 21/12/2001, deposition: 17/09/2001, last revision: 24/02/2009
Authors Nakama, T.search; Nureki, O.search; Yokoyama, S.search; RIKEN Structural Genomics/Proteomics Initiative (RSGI)search
Primary citation Structural basis for the recognition of isoleucyl-adenylate and an antibiotic, mupirocin, by isoleucyl-tRNA synthetase.
J.BIOL.CHEM.search vol:276, pag:47387-47393 (2001) [PubMed ID 11584022 ]search
Keywords aminoacyl-tRNA synthetasesearch, RIKEN Structural Genomics/Proteomics Initiativesearch, RSGIsearch, Structural Genomicssearch, LIGASEsearch
EC 6.1.1.5 ExPASy BRENDA search (A)
Organism Thermus thermophilus 274search(A)
UniProt Isoleucyl-tRNA synthetase (EC 6.1.1.5) (Isoleucine--tRNA ligase) (IleRS) P56690search (A)
Related entries 1jzq
Polymers
Id Name Type UniProt Residues Observed
A Isoleucyl-tRNA synthetase Protein P56690 (SYI_THET8)search
 821 100%
Heterogens
Id Name Ligands
A ZINC ION ZN search
A MUPIROCIN MRC search
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