Xray Structure of Grb2 SH2 Domain
The structure was published by Nioche, P., Liu, W.Q., Broutin, I., et al., Roques, B., Garbay, C., and Ducruix, A., in 2002 in a paper entitled "Crystal structures of the SH2 domain of Grb2: highlight on the binding of a new high-affinity inhibitor." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.75 Å and deposited in 2001.
The experimental data on which the structure is based was also deposited.
The PDB entry contains the structure of GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2. This molecule has the UniProt identifier P62993 (GRB2_HUMAN). The sample contained 96 residues which is < 90% of the natural sequence. Out of 96 residues 96 were observed and are deposited in the PDB.
The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: