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Neurospora crassa 3-carboxy-cis,cis-mucoante lactonizing enzyme

The structure was published by Kajander, T., Merckel, M.C., Thompson, A., et al., Mazur, P., Kozarich, J.W., and Goldman, A., in 2002 in a paper entitled "The structure of Neurospora crassa 3-carboxy-cis,cis-muconate lactonizing enzyme, a beta propeller cycloisomerase." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.5 Å and deposited in 2001.

The experimental data on which the structure is based was also deposited.

This PDB entry contains multiple copies of the structure of CARBOXY-CIS,CIS-MUCONATE CYCLASE.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A CARBOXY-CIS,CIS-MUCONATE CYCLASE P38677 (2-366) (CMLE_NEUCR)search Neurospora crassa OR74Asearch 100% 365 100%
B CARBOXY-CIS,CIS-MUCONATE CYCLASE P38677 (2-366) (CMLE_NEUCR)search Neurospora crassa OR74Asearch 100% 365 100%
C CARBOXY-CIS,CIS-MUCONATE CYCLASE P38677 (2-366) (CMLE_NEUCR)search Neurospora crassa OR74Asearch 100% 365 100%
D CARBOXY-CIS,CIS-MUCONATE CYCLASE P38677 (2-366) (CMLE_NEUCR)search Neurospora crassa OR74Asearch 100% 365 100%
E CARBOXY-CIS,CIS-MUCONATE CYCLASE P38677 (2-366) (CMLE_NEUCR)search Neurospora crassa OR74Asearch 100% 365 100%
F CARBOXY-CIS,CIS-MUCONATE CYCLASE P38677 (2-366) (CMLE_NEUCR)search Neurospora crassa OR74Asearch 100% 365 100%
G CARBOXY-CIS,CIS-MUCONATE CYCLASE P38677 (2-366) (CMLE_NEUCR)search Neurospora crassa OR74Asearch 100% 365 100%
H CARBOXY-CIS,CIS-MUCONATE CYCLASE P38677 (2-366) (CMLE_NEUCR)search Neurospora crassa OR74Asearch 100% 365 100%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P38677 (2 - 366) CARBOXY-CIS,CIS-MUCONATE CYCLASE Neurospora crassa

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A, B, C, D, E, F, G, H (P38677) 3-carboxy-cis,cis-mucoante lactonizing enzymesearch YVTN repeat-like/Quinoprotein amine dehydrogenasesearch PF10282: Lactonase, 7-bladed beta-propellersearch

Chain ID Biological process (GO) Molecular function (GO)
A, B, C, D, E, F, G, H (P38677) beta-ketoadipate pathwaysearch carboxy-cis,cis-muconate cyclase activitysearch isomerase activitysearch

Chain InterPro annotation
A, B, C, D, E, F, G, H WD40/YVTN repeat-like-containing domainsearch Lactonase, 7-bladed beta propellersearch